AT3G04580 EIN4 ETHYLENE INSENSITIVE 4 (EIN4); FUNCTIONS IN: ethylene binding, protein histidine kinase activity, receptor activity, glycogen synthase kinase 3 activity; INVOLVED IN: negative regulation of ethylene mediated signaling pathway; LOCATED IN: endomembrane system, endoplasmic reticulum membrane, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, homodimeric (InterPro:IPR009082), CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789), Signal transduction histidine kinase, hybrid-type, ethylene sensor (InterPro:IPR014525), Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661), ATPase-like, ATP-binding domain (InterPro:IPR003594), GAF (InterPro:IPR003018); BEST Arabidopsis thaliana protein match is: Signal transduction histidine kinase, hybrid-type, ethylene sensor (TAIR:AT3G23150.1); Has 63350 Blast hits to 57717 proteins in 2870 species: Archae - 286; Bacteria - 55528; Metazoa - 15; Fungi - 1532; Plants - 2041; Viruses - 18; Other Eukaryotes - 3930 (source: NCBI BLink). ETHYLENE INSENSITIVE 4