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    <dc:description xml:lang="en">&lt;title&gt;RIB00108&lt;/title&gt;&lt;meta http-equiv="content-type" content="text/html; charset=UTF-8"&gt;&lt;table width="100%"&gt;&lt;tbody&gt;&lt;tr&gt;&lt;td colspan="3" scope="col" style="background-color: rgb(0, 0, 127);" height="20" width="100%"&gt;&lt;strong&gt;&lt;span style="font-size: 16px; font-family: Verdana; color: rgb(255, 0, 0);"&gt;&lt;em&gt; 　HATODAS&lt;/em&gt;　Heavy-atom Database System&lt;/span&gt;&lt;/strong&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/tbody&gt;&lt;/table&gt;&lt;table width="100%"&gt;&lt;tbody&gt;&lt;tr&gt;&lt;td scope="col" rowspan="3" width="5"&gt;&lt;br&gt;&lt;/td&gt;&lt;td scope="col" rowspan="3" width="200"&gt;&lt;br&gt;&lt;/td&gt;&lt;td scope="col" rowspan="3" width="20"&gt;&lt;br&gt;&lt;/td&gt;&lt;td scope="col" align="left" valign="top" width="100%"&gt;&lt;span style="font-family: Verdana; font-size: 12px; color: rgb(0, 0, 127);"&gt;&lt;a title="HATODAS Home" href="http://hatodas.harima.riken.go.jp/" target="_blank"&gt;&lt;em&gt;Heavy-atom Database System&lt;/em&gt;&lt;/a&gt; (HATODAS) is a WWW-based tool designed to assist the heavy-atom derivatization of proteins. The conventional procedure for the preparation of derivatives is usually a time-consuming `trial-and-error' process. The present program provides a solution for this problem using a database of known heavy-atom derivatives. A database search suggests potential heavy-atom reagents for any target protein based on its amino-acid sequence and crystallization conditions. A mining of the database identified 93 preferred motifs for heavy-atom binding. The motifs are observed frequently at the actual heavy-atom-binding sites encountered in the process of structure determination.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" scope="col" height="20" width="100%"&gt;&lt;strong&gt;&lt;span style="font-size: 12px; background-color: rgb(255, 255, 255); font-family: Verdana;"&gt;&lt;a href="http://metadb.riken.jp/metadb/db/SciNetS_rib108i/http://metadb.riken.jp/db/SciNetS_rib108i/crib108s4i"&gt;HATODAS ver.1&lt;/a&gt;&lt;/span&gt;&lt;/strong&gt;&amp;nbsp;&amp;nbsp;&lt;span style="font-family: Verdana; font-size: 9px; color: rgb(0, 0, 127);"&gt;&lt;a href="http://scripts.iucr.org/cgi-bin/paper?S0907444905019670"&gt;Heavy-atom Database System: a tool for the preparation of heavy-atom derivatives of protein crystals based on amino-acid sequence and crystallization conditions.  Acta Crystallographica Section D61, 1302-1305, (2005).&lt;/a&gt;&lt;/span&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" scope="col" height="20" width="100%"&gt;&lt;strong&gt;&lt;span style="font-size: 12px; background-color: rgb(255, 255, 255); font-family: Verdana;"&gt;&lt;a href="http://metadb.riken.jp/metadb/db/SciNetS_rib108i/http://metadb.riken.jp/db/SciNetS_rib108i/crib108s5i"&gt;HATODAS ver.2&lt;/a&gt;&lt;/span&gt;&lt;/strong&gt;&amp;nbsp;&amp;nbsp;&lt;span style="font-family: Verdana; font-size: 9px; color: rgb(0, 0, 127);"&gt;&lt;a href="http://scripts.iucr.org/cgi-bin/paper?he5418"&gt;HATODAS II - heavy-atom database system with potentiality scoring.  Journal of Applied Crystallography, 42, 540-544. (2009).&lt;/a&gt;&lt;/span&gt;&lt;!--&lt;a href="/sw/links/en/crib108s4i/"&gt;HATODAS ver.1&lt;/a&gt;&amp;nbsp;&amp;nbsp;&lt;a href="/sw/links/en/crib108s5i/"&gt;HATODAS ver.2&lt;/a&gt;--&gt;&lt;!--&lt;a href="http://hatodas.harima.riken.go.jp/hatodas_v1/cgi-bin/input.cgi"&gt;HATODAS ver.1&lt;/a&gt;&amp;nbsp;&amp;nbsp;&lt;a href="http://hatodas.harima.riken.go.jp/hatodas_v2/query/queryheavy.jsp"&gt;HATODAS ver.2&lt;/a&gt;--&gt;&lt;!--&lt;a href="javascript:panelOpenById('CRIB00108U000001');"&gt;RIKEN Heavy Atom Record&lt;/a&gt;--&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/tbody&gt;&lt;/table&gt;</dc:description>
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    <dc:description xml:lang="ja">&lt;title&gt;RIB00108&lt;/title&gt;&lt;meta http-equiv="content-type" content="text/html; charset=UTF-8"&gt;&lt;table width="100%"&gt;&lt;tbody&gt;&lt;tr&gt;&lt;td colspan="3" scope="col" style="background-color: rgb(0, 0, 127);" height="20" width="100%"&gt;&lt;strong&gt;&lt;span style="font-size: 16px; font-family: Verdana; color: rgb(255, 0, 0);"&gt;&lt;em&gt; 　HATODAS&lt;/em&gt;　Heavy-atom Database System&lt;/span&gt;&lt;/strong&gt;&lt;/td&gt;&lt;/tr&gt;&lt;/tbody&gt;&lt;/table&gt;&lt;table width="100%"&gt;&lt;tbody&gt;&lt;tr&gt;&lt;td scope="col" rowspan="3" width="5"&gt;&lt;br&gt;&lt;/td&gt;&lt;td scope="col" rowspan="3" width="200"&gt;&lt;br&gt;&lt;/td&gt;&lt;td scope="col" rowspan="3" width="20"&gt;&lt;br&gt;&lt;/td&gt;&lt;td scope="col" align="left" valign="top" width="100%"&gt;&lt;span style="font-family: Verdana; font-size: 12px; color: rgb(0, 0, 127);"&gt;&lt;a title="HATODAS Home" href="http://hatodas.harima.riken.go.jp/" target="_blank"&gt;&lt;em&gt;Heavy-atom Database System&lt;/em&gt;&lt;/a&gt; (HATODAS) is a WWW-based tool designed to assist the heavy-atom derivatization of proteins. The conventional procedure for the preparation of derivatives is usually a time-consuming `trial-and-error' process. The present program provides a solution for this problem using a database of known heavy-atom derivatives. A database search suggests potential heavy-atom reagents for any target protein based on its amino-acid sequence and crystallization conditions. A mining of the database identified 93 preferred motifs for heavy-atom binding. The motifs are observed frequently at the actual heavy-atom-binding sites encountered in the process of structure determination.&lt;/span&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" scope="col" height="20" width="100%"&gt;&lt;strong&gt;&lt;span style="font-size: 12px; background-color: rgb(255, 255, 255); font-family: Verdana;"&gt;&lt;a href="http://metadb.riken.jp/metadb/db/SciNetS_rib108i/http://metadb.riken.jp/db/SciNetS_rib108i/crib108s4i"&gt;HATODAS ver.1&lt;/a&gt;&lt;/span&gt;&lt;/strong&gt;&amp;nbsp;&amp;nbsp;&lt;span style="font-family: Verdana; font-size: 9px; color: rgb(0, 0, 127);"&gt;&lt;a href="http://scripts.iucr.org/cgi-bin/paper?S0907444905019670"&gt;Heavy-atom Database System: a tool for the preparation of heavy-atom derivatives of protein crystals based on amino-acid sequence and crystallization conditions.  Acta Crystallographica Section D61, 1302-1305, (2005).&lt;/a&gt;&lt;/span&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;&lt;tr&gt;&lt;td colspan="3" scope="col" height="20" width="100%"&gt;&lt;strong&gt;&lt;span style="font-size: 12px; background-color: rgb(255, 255, 255); font-family: Verdana;"&gt;&lt;a href="http://metadb.riken.jp/metadb/db/SciNetS_rib108i/http://metadb.riken.jp/db/SciNetS_rib108i/crib108s5i"&gt;HATODAS ver.2&lt;/a&gt;&lt;/span&gt;&lt;/strong&gt;&amp;nbsp;&amp;nbsp;&lt;span style="font-family: Verdana; font-size: 9px; color: rgb(0, 0, 127);"&gt;&lt;a href="http://scripts.iucr.org/cgi-bin/paper?he5418"&gt;HATODAS II - heavy-atom database system with potentiality scoring.  Journal of Applied Crystallography, 42, 540-544. (2009).&lt;/a&gt;&lt;/span&gt;&lt;!--&lt;strong&gt;&lt;span style="font-size: 12px; background-color: rgb(255, 255, 255); font-family: Verdana;"&gt;--&gt;&lt;!--&lt;a href="javascript:panelOpenById('CRIB00108U000001');"&gt;RIKEN Heavy Atom Record&lt;/a&gt;--&gt;&lt;!--&lt;a href="/sw/links/ja/crib108s4i/"&gt;HATODAS ver.1&lt;/a&gt;&amp;nbsp;&amp;nbsp;&lt;a href="/sw/links/ja/crib108s5i/"&gt;HATODAS ver.2&lt;/a&gt;--&gt;&lt;!--&lt;a href="http://hatodas.harima.riken.go.jp/hatodas_v1/cgi-bin/input.cgi"&gt;HATODAS ver.1&lt;/a&gt;&amp;nbsp;&amp;nbsp;&lt;a href="http://hatodas.harima.riken.go.jp/hatodas_v2/query/queryheavy.jsp"&gt;HATODAS ver.2&lt;/a&gt;--&gt;&amp;nbsp;&lt;/span&gt;&lt;/strong&gt;&amp;nbsp;&amp;nbsp;&lt;/td&gt;&lt;/tr&gt;&lt;/tbody&gt;&lt;/table&gt;</dc:description>
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