<p>This group represents a DNA recombination repair protein, BRCA2 type. The BRCA2 tumour suppressor has been implicated in the maintenance of chromosomal stability through a function in DNA repair, probably in conjunction with the Rad51 recombinase. We propose that impaired homology-directed repair caused by BRCA2 deficiency leads to chromosomal instability and, possibly, tumorigenesis, through lack of repair or misrepair of DNA damage[<cite idref="PUB00014589"/> , <cite idref="PUB00014590"/>, <cite idref="PUB00014591"/>].</p> DNA recombination and repair protein, BRCA2