Glycosyl hydrolases 38, C-terminal <p>O-Glycosyl hydrolases <db_xref db="EC" dbkey="3.2.1."/> are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [<cite idref="PUB00004870"/>, <cite idref="PUB00005266"/>]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.</p><p>Glycoside hydrolase family 38 <db_xref db="CAZY" dbkey="GH38"/> comprises enzymes with only one known activity; alpha-mannosidase (<db_xref db="EC" dbkey="3.2.1.24"/>) (<db_xref db="EC" dbkey="3.2.1.114"/>). This domain is found at the C terminus of glycosyl hydrolases from family 38.</p>