<p>This domain is found towards the C-terminal region of various aldolase enzymes. It consists of five alpha-helices, four of which form an antiparallel helical bundle that plugs the C terminus of the N-terminal TIM barrel domain [<cite idref="PUB00016385"/>]. The communication domain is thought to play an important role in the heterodimerisation of the enzyme [<cite idref="PUB00016385"/>]. </p><p>Members of this entry heterodimerise with members of <db_xref db="INTERPRO" dbkey="IPR003361"/> to form a bifunctional aldolase-dehydrogenase [<cite idref="PUB00016385"/>].</p> DmpG-like communication