<p>O-Glycosyl hydrolases <db_xref db="EC" dbkey="3.2.1."/> are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [<cite idref="PUB00004870"/>, <cite idref="PUB00005266"/>]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.</p><p>This entry represents the all-beta domain that is found in several members of the glycosyl hydrolase family 13. It is usually located C-terminal to the catalytic beta/alpha barrel domain. This structure of this domain has been found to be a Greek key beta-sheet fold [<cite idref="PUB00023681"/>, <cite idref="PUB00026212"/>, <cite idref="PUB00027695"/>, <cite idref="PUB00027696"/>].</p><p>More information about this protein can be found at Protein of the Month: alpha-Amylase [<cite idref="PUB00027697"/>].</p> Glycosyl hydrolase, family 13, all-beta