<p>Members of this family are examples of pyruvate oxidase (<db_xref db="EC" dbkey="1.2.3.3"/>), an enzyme with FAD and TPP as cofactors that catalyses the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase (<db_xref db="EC" dbkey="1.2.2.2"/>) as in <taxon tax_id="562">Escherichia coli</taxon> PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name.</p> Pyruvate oxidase