<p>5'-3'-exoribonucleases are enzymes that degrade RNA by removing terminal nucleotides from the 5' end. Hydrolytic exoribonucleases, to which this entry belongs, produce nucleotide monosphosphates. An exosome and a 5'-3'-exoribonuclease are important in the degradation of very unstable transcripts [<cite idref="PUB00043318"/>].</p><p>The loss of XRN4/EIN5, a 5'-3' exoribonuclease, and ABH1/CBP80, a subunit of the mRNA cap binding complex, results in Arabidopsis plants manifesting myriad developmental defects [<cite idref="PUB00043319"/>], suggesting that this enzyme is not only important for RNA processing.</p><p>5'-3' exoribonuclease type 2 occurs in animal, plant and fungal lineages.</p> 5'-3' exoribonuclease 2