<p> This entry represents plant-type phosphatidylinositol-4-phosphate 5-kinase (PIP5K; <db_xref db="EC" dbkey="2.7.1.68"/>), which plays an essential role in coordinating plant growth, especially in response to environmental factors. This enzyme phosphorylates phosphatidylinositol-4-phosphate to produce phosphatidylinositol-4,5-bisphosphate as a precursor of two second messengers, inositol-1,4,5-triphosphate and diacylglycerol, and as a regulator of many cellular proteins involved in signal transduction and cytoskeletal organisation. This enzyme is involved in flowering, and may suppress floral initiation by modifying the expression of genes related to floral induction. It appears to be stress-induced [<cite idref="PUB00044688"/>, <cite idref="PUB00044689"/>].</p> Phosphatidylinositol-4-phosphate 5-kinase, plant