<p>Fe/S biogenesis protein NfuA is involved in iron-sulphur cluster biogenesis under severe conditions such as iron starvation or oxidative stress. It binds a 4Fe-4S cluster and can transfer this cluster to apoproteins, thereby intervening in the maturation of Fe/S proteins. This protein could also act as a scaffold/chaperone for damaged Fe/S proteins. </p><p>Fe/S biogenesis protein NfuA is required for <taxon tax_id="562">Escherichia coli</taxon> to sustain oxidative stress and iron starvation, it is also necessary for the use of extracellular DNA as the sole source of carbon and energy. </p> Fe/S biogenesis protein, NfuA