This domain is always found associated with (<db_xref db="INTERPRO" dbkey="IPR000583"/>). Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B (<db_xref db="EC" dbkey="6.3.5.4"/>) catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine.The three-dimensional architecture of the N-terminal domain of asparagine synthetase B is similar to that observed for glutamine phosphoribosylpyrophosphate amidotransferase while the molecular motif of the C-domain is reminiscent to that observed for GMP synthetase [<cite idref="PUB00006460"/>]. Asparagine synthase