<p>Glucose-6-phosphate dehydrogenase (G6PD) [<cite idref="PUB00001438"/>] catalyses the first step in the pentose pathway, the reduction of glucose-6-phosphate to gluconolactone 6-phosphate. A lysine residue has been identified as a reactive nucleophile associated with the activity of the enzyme [<cite idref="PUB00045349"/>]. The sequence around this lysine is totally conserved from bacterial to mammalian G6PD's and is used as the pattern to identify the proteins associated with this entry.</p> Glucose-6-phosphate dehydrogenase, active site