<p>The stromal antigens or stromalins are a group of highly conserved nuclearproteins, originally identified from a murine bone marrows stromal cell line.Stromalins are represented in several organisms from yeast to humans and arecharacterised by the stromalin conservative domain (SCD), an 86 amino acidmotif found in all proteins of the family described to date [<cite idref="PUB00052629"/>].</p><p>Some proteins known to contain a stromalin conservative domain are listed below:</p><ul><li> Vertebrate cohesin subunits SA-1, -2 and -3 (Stag1, 2 and 3), components of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication.</li><li> Human STAG3-like protein.</li><li> Yeast cohesin subunit SCC3, a component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication.</li><li> Fission yeast meiotic recombination protein Rec11.</li></ul> Stromalin conservative domain