<p> This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in <taxon tax_id="562">Escherichia coli</taxon>. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the transcription-repair-coupling factor (TRCF) which releases RNAP and the truncated transcript.</p> Transcription-repair-coupling factor domain