SWIRM <p>The SWIRM domain is a small alpha-helical domain of about 85 amino acid residues found in eukaryotic chromosomal proteins. It is named after the proteins SWI3, RSC8 and MOIRA in which it was first recognised. This domain is predicted to mediate protein-protein interactions in the assembly of chromatin-protein complexes. The SWIRM domain can be linked to different domains, such as the ZZ-type zinc finger (<db_xref db="INTERPRO" dbkey="IPR000433"/>), the Myb DNA-binding domain (<db_xref db="INTERPRO" dbkey="IPR001005"/>), the HORMA domain (<db_xref db="INTERPRO" dbkey="IPR003511"/>), the amino-oxidase domain, the chromo domain (<db_xref db="INTERPRO" dbkey="IPR000953"/>), and the JAB1/PAD1 domain.</p>