<a href='https://brc.riken.jp/mus/pcr01130'>Genotyping protocol -PCR-</a>
Chicago Univ.
University of Chicago
条件を付加しない。
CGT-deficient mice fail to make galactolipid galactocerebroside and its sulfated derivative that are normal myelin constitutents. Mutant mice exhibit tremors, ataxia, progressive hindlib paralysis and vaculoe formation in ventral spinal cord due to abnormal myelin sheath.B6.129P2-Ugt8a<tm1Pop>. Ceramide galactosyltransferase, CGT is a key enzyme in the biosynthesis of galactocerebroside, GalC. Homozygous mutant mice for CGT gene show tremor, ataxia progressive hind limb paralysis and extensiv vacuolation of the ventral spinal cord.
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Brian Popko
Brian Popko
mouse Ceramide galactosyltransferase (CGT) genomic DNA, E. coli neo
C(3〜6か月)
Ceramide galactosyltransferase (CGT)-deficient mice
Ceramide galactosyltransferase (CGT)-deficient mice
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
RBRC01130
B6.129P2-Ugt8a<tm1Pop>/Rbrc
Developed by Dr. Brain Popko, University of North Carolina in 1996.
CGT-deficient mice fail to make galactolipid galactocerebroside and its sulfated derivative that are normal myelin constitutents. Mutant mice exhibit tremors, ataxia, progressive hindlib paralysis and vaculoe formation in ventral spinal cord due to abnormal myelin sheath. B6.129P2-Ugt8a<tm1Pop>. Ceramide galactosyltransferase, CGT is a key enzyme in the biosynthesis of galactocerebroside, GalC. Homozygous mutant mice for CGT gene show tremor, ataxia progressive hind limb paralysis and extensiv vacuolation of the ventral spinal cord.
Ceramide galactosyltransferase (CGT)-deficient mice
C (3-6 months)
hetero x heterohomozygous mice are infertile.行動の異常がある形態の異常・奇形がある繁殖成績が低いホモで不妊/死亡
BK4 [129P2/OlaHsd]
hetero x hetero homozygous mice are infertile. 行動の異常がある 形態の異常・奇形がある 繁殖成績が低い ホモで不妊/死亡
Cell Biology Research
No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Neurobiology Research
Sibling Mating