This transgenic mice has a diphtheria toxin recepotr (DTR) and GFP fusion gene under under the control of the mouse Itgax promoer. The dendritic cells of this strain were transiently disrupted with DT inducible system. C(3〜6か月) RBRC01659 mouse Itgax promoter, human heparin-binding EGF-like growth factor(hbEGF), jellyfish Green Fluorescence Protein (GFP) cDNA Fluorescent Proteins/lacZ System <a href='https://brc.riken.jp/mus/pcr01659'>Genotyping protocol -PCR-</a> true The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Research Purpose only. The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEVELOPER (Dr. Dan Littman). ジフテリアトキシンを投与することで樹状細胞を消去できる系統です。 C (3-6 months) 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。<br>研究成果の公表にあたって謝辞の表明を必要とする。<br>学術研究目的に限る。事前に開発者(Dr. Dan Littman) に連絡し、必要な手続きを行い、使用許可を得る。 Keio University C.FVB-Tg(Itgax-DTR/EGFP)57Lan/Rbrc C.FVB-Tg(Itgax-DTR/EGFP)57Lan/Rbrc Shigeo KOYASU 慶應義塾大学 D. Littman が作製したもので、これも C57BL/6 と BALB/c バックの2系統あります。ただし、これらは今は Jackson にあります (stock # 004509 と # 004512) 。 Developed by Steffen Jung in 2002. DTR/GFP under the control of the mouse Itgax promoer. The DTR/GFP1 fusion gene under the mouse Itgax promoter was injected into the pronuclei of FVB/N fertilized eggs. 小安 重夫 Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li><li>GFP Transfer License (<A HREF="https://web.brc.riken.jp/ja/method/link/gfp_conclude">Japanese</A> / <A HREF="https://web.brc.riken.jp/en/method/link/gfp_conclude">English</A>)<br>Please fill in the <A HREF="https://web.brc.riken.jp/en/wp-content/uploads/form/gfp_schedule_a.doc">Schedule A</A>, and submit two signed copies to us together with two signed copies of RIKEN BRC's MTA. Please also read <A HREF="https://web.brc.riken.jp/en/wp-content/uploads/form/gfp_schedule_b.doc"> Schedule B</A>. </li></ol><A HREF="https://www.ims.riken.jp/labo/43/index.html" target="_blank">Lab HP</A>