C (3-6 months) Univ. Tokyo mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo resistance gene, mouse Tcea1 genomic DNA E14 ES細胞を用いて、ヘテロ欠損細胞を樹立。キメラマウス作成後、C57BL6/J-Jcl (Japan CLEA)へ戻し交配した。現在N14. Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://meneki.f.u-tokyo.ac.jp/" target="_blank">Lab HP (Japanese)</A> S-II (+/-) mouse S-II (+/-) mouse The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Cell. Biol., 26, 3194-3203 (2006).The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers.<br>The DEPOSITOR should be a co-author in articles when the RECIPIENTs publish their data using these mice for 2 year after provided to the RIKEN BRC.<br>The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.<br>Transfer of the BIOLOGICAL RESOURCE to the third party from the RECIPIENT will never be done without a prior permission of the DEPOSITOR. ホモで不妊／死亡。ヘテロ欠損マウスの繁殖においては特に問題はない。 ホモ欠損マウスは13.5〜14.5dpcで胎生致死。 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Mol. Cell. Biol., 26, 3194-3203 (2006).<br>公表を前提とした学術研究に限る。<br>寄託後2年間は寄託者との共同研究とする。<br>本件リソースを使用した研究成果に基づき特許等の申請を行う場合は、別途協議を行う。<br>寄託者の承諾なしに第三者への分与はしない。 true C（3〜6か月） B6.129P2-Tcea1<tm1Skmz>/SkmzRbrc B6.129P2-Tcea1<tm1Skmz>/SkmzRbrc RBRC01819 E14 [129P2/OlaHsd] Kazuhisa SEKIMIZU 国立大学法人東京大学 関水　和久