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    <ns1:strainDevelopment xml:lang="ja">開発者／機関：岩井なおみ先生（大阪大学）開発年：2001年B6C3F1の受精卵にmicrionjectionして作出。得られたTgマウスをB6C3F1と交配維持。現在の世代数は不明。</ns1:strainDevelopment>
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    <dc:description xml:lang="ja">Nodal遺伝子上流領域(-9.5 to -8.7kb)にhsp68-lacZを結合させた配列を持つ。node特異的にlacZ遺伝子が発現する。</dc:description>
    <ns1:strainDevelopment xml:lang="ja">開発者／機関：岩井なおみ先生（大阪大学） 開発年：2001年 B6C3F1の受精卵にmicrionjectionして作出。得られたTgマウスをB6C3F1と交配維持。 現在の世代数は不明。</ns1:strainDevelopment>
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    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <ns6:brs_depositorOrganization xml:lang="en">Osaka Univ.</ns6:brs_depositorOrganization>
    <ns6:brs_depositor xml:lang="en">Hiroshi HAMADA</ns6:brs_depositor>
    <ns1:isRecombinant rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean"
    >true</ns1:isRecombinant>
    <ns1:colonyMaintenance xml:lang="en">Carrier x Noncarrier or Crossing to Jcl:B6C3F1 Tg mice are viable and fertile.</ns1:colonyMaintenance>
    <ns6:brs_hasAppearance rdf:parseType="Resource">
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    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns4:addinfo>
    <ns4:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;研究成果の公表にあたって譲渡者の指定する文献を引用する。Genes Dev.,17, 1207-1212 (2003).</ns4:termsAndConditions>
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    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/straintype_2"/>
    <ns6:brs_hasAppearance rdf:parseType="Resource">
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    <skos:altLabel xml:lang="ja">Nodal NDE lacZ (H11)</skos:altLabel>
    <skos:altLabel xml:lang="en">Nodal NDE lacZ (H11)</skos:altLabel>
    <ns6:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_3"/>
    <ns1:strainDevelopment xml:lang="en">Developed by Drs. Naomi Iwai and Hiroshi Hamada at Oasaka University in 2001.</ns1:strainDevelopment>
    <ns5:organism rdf:parseType="Resource">
    </ns5:organism>
    <ns1:colonyMaintenance xml:lang="en">Carrier x Noncarrier or Crossing to Jcl:B6C3F1Tg mice are viable and fertile.</ns1:colonyMaintenance>
    <ns4:application>Developmental Biology Research</ns4:application>
    <ns6:brs_hasAllele rdf:resource="http://metadb.riken.jp/db/mgi_rdf/MGI:3641198"/>
    <dcterms:identifier>RBRC02216</dcterms:identifier>
    <ns4:resourceTypeLink rdf:resource="http://metadb.riken.jp/terms/xsearch#resource_type_transgene"/>
    <rdfs:seeAlso rdf:resource="http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC02216"/>
    <ns11:citesAsAuthority rdf:resource="http://rdf.ncbi.nlm.nih.gov/pubmed/12730124"/>
    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
    <ns6:brs_depositor xml:lang="ja">濱田　博司</ns6:brs_depositor>
    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainType_24"/>
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    <ns7:SIO_001279 rdf:parseType="Resource">
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    <ns9:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
    <ns6:brs_depositedBy rdf:parseType="Resource">
    </ns6:brs_depositedBy>
    <ns1:donorDNA>E. coli lacZ, mouse nodal node-specific expression enhancer, hsp68 promoter</ns1:donorDNA>
    <dc:description xml:lang="ja">Nodal遺伝子上流領域(-9.5 to -8.7kb)にhsp68-lacZを結合させた配列を持つ。,node特異的にlacZ遺伝子が発現する。</dc:description>
    <ns1:colonyMaintenance xml:lang="ja">ヘテロ×B6C3F1   (ブリーダーの指定はなし）</ns1:colonyMaintenance>
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    <ns6:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_2"/>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
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    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
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    <foaf:depiction rdf:resource="https://mus.list.brc.riken.jp/ja/wp-content/image_s/02216-P-1091-01.jpg"/>
    <rdfs:label>STOCK Tg(nodalNDE-hsp68-lacZ)H11Hmd</rdfs:label>
    <rdfs:label xml:lang="en">STOCK Tg(nodalNDE-hsp68-lacZ)H11Hmd</rdfs:label>
    <ns5:organism rdf:parseType="Resource">
    </ns5:organism>
    <dc:description xml:lang="en">This transgenic mice carry a hsp68-lacZ gene under control of a 0.8-kb region upstream of Nodal coding sequences (-9.5 and -8.7 kb) containing the node-specific enhancer (NDE).  X-gal staining around the node can be detected in embryos at early somite stages.</dc:description>
    <ns1:expectedDelivery xml:lang="ja">C（3〜6か月）</ns1:expectedDelivery>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
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    <ns6:brs_hasAppearance rdf:parseType="Resource">
    </ns6:brs_hasAppearance>
    <ns4:termsAndConditions xml:lang="en">In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev.,17, 1207-1212 (2003).</ns4:termsAndConditions>
    <ns6:brs_depositorOrganization xml:lang="ja">国立大学法人大阪大学</ns6:brs_depositorOrganization>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <dcterms:references rdf:resource="http://identifiers.org/pubmed/12730124"/>
    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_8"/>
    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_6"/>
    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_4"/>
    <ns6:brs_depositedBy rdf:parseType="Resource">
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  </rdfs:Class>
  <rdf:Description rdf:about="http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018996">
    <ns6:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC02216"/>
  </rdf:Description>
  <rdf:Description rdf:about="http://metadb.riken.jp/db/rikenbrc_mouse/HealthCertificate_114042">
    <ns6:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC02216"/>
  </rdf:Description>
  <rdf:Description rdf:about="http://metadb.riken.jp/db/rikenbrc_mouse/HealthCertificate_5325">
    <ns6:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC02216"/>
  </rdf:Description>
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