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    <ns5:termsAndConditions xml:lang="ja">条件を付加する。利用者は事前に寄託者の提供承諾書を得る。&lt;br&gt;研究成果の公表にあたって寄託者の指定する文献を引用する。Proc. Natl. Acad. Sci. USA, 99, 3657-3662 (2002).&lt;br&gt;利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、寄託者と別途協議を行う。</ns5:termsAndConditions>
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    <ns5:addinfo>&lt;a href='https://brc.riken.jp/mus/pcr02251'&gt;Genotyping protocol -PCR-&lt;/a&gt;</ns5:addinfo>
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    <ns0:brs_depositor xml:lang="ja">高島　成二</ns0:brs_depositor>
    <ns5:termsAndConditions xml:lang="en">The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA, 99, 3657-3662 (2002).The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.</ns5:termsAndConditions>
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    <dc:description xml:lang="ja">Nrp2遺伝子のノックアウトマウス。ATGを含むエクソン1とその下流の一部がlacZ-neoカセットで置換されている。ホモマウスは血管、神経系の異常により胎生期もしくは生後すぐに死亡する。</dc:description>
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    <ns5:application>Neurobiology Research</ns5:application>
    <dc:description xml:lang="en">Neuropilin 2 gene knockout mice.  Exon1 and part of the downstream intron including ATG was replaced with a lacZ-neo cassette.  Neuropilin 2 expression was successfully stained with lacZ in various tissue using heterozygous mice.  Homozygous mutant mice have vascular and neuronal abnormality and die in uterus or just after birth.</dc:description>
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    <ns5:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Approval form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns5:addinfo>
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    <ns5:application>Fluorescent Proteins/lacZ System</ns5:application>
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    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
    <ns0:brs_depositorOrganization xml:lang="ja">国立大学法人大阪大学</ns0:brs_depositorOrganization>
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    <ns1:strainDevelopment xml:lang="en">Developed by Seiji Takashima, Osaka University Graduate School of Medicine in 1998.  CGR8 ES cells were used.</ns1:strainDevelopment>
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    <ns1:strainDevelopment xml:lang="ja">大阪大学大学院医学系研究科・高島成二先生（1998）。CGR8 ES細胞由来。</ns1:strainDevelopment>
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