Casp130 (Bcar1) 遺伝子のエクソン2 (SH3 domainをコード) をloxPで挟んだfloxアレルと乳腺特異的BLG (βlactoglobulin) -Creをもつダブルミュータントマウス。通常の維持繁殖には特に問題ない。ホモKOマウス、Tgマウスともに生存性、繁殖性あり。繁殖成績はあまり良くない。 FLP/frt system Cre/loxP system 条件を付加する。利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。 Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. 広島大学原爆放射線医科学研究所・本田浩章先生（2003）。 Cell Biology Research Developed by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2003. Cas-ex2<flox/flox>-Tg(BLG-Cre) Cas-ex2<flox/flox>-Tg(BLG-Cre) 国立大学法人広島大学 Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://www.twmu.ac.jp/ILA/" target="_blank">Lab HP (Japanese)</A> Casp130 (Bcar1) 遺伝子のエクソン2 (SH3 domainをコード) をloxPで挟んだfloxアレルと乳腺特異的BLG (βlactoglobulin) -Creをもつダブルミュータントマウス。通常の維持繁殖には特に問題ない。ホモKOマウス、Tgマウスともに生存性、繁殖性あり。繁殖成績はあまり良くない。, E14 [129P2/OlaHsd] B6.Cg-p130Cas<tm1.2Homy> Tg(BLG-cre)1Homy B6.Cg-p130Cas<tm1.2Homy> Tg(BLG-cre)1Homy C (3-6 months) <a href='https://brc.riken.jp/mus/pcr02295'>Genotyping protocol -PCR-</a> phage P1 loxP sites, yeast (Saccharomyces cerevisiae) FRT site, mouse Cas genomic DNA, sheep BLG genomic DNA, phage P1 Cre-recombinase Hiroaki HONDA Hiroshima Univ. RBRC02295 C（3〜6か月） KO: Homozygote x Homozygote; Tg: Carrier x Carrier [or Crossing to C57BL/6NCrlCrlj] KO: Homozygote x Homozygote; Tg: Carrier x Carrier [or Crossing to C57BL/6NCrlCrlj] true 本田　浩章 Casp130 (Bcar1) gene exon 2 floxed and BLG (beta lactoglobulin)-cre double mutant mice. Viable and fertile, but the reproductive performance is not so good.