cav3-KO/32, Cav3 KO#32
cav3-KO/32, Cav3 KO#32
戻し交配せず、兄妹交配Background系統：129 and B6 mixed
D（6か月以上）
E coli neo, mouse caveolin-3(Cav3) genomic DNA
Toshikuni SASAOKA
戻し交配せず、兄妹交配 Background系統：129 and B6 mixed
Cav3 (caveolin 3) 遺伝子のノックアウトマウス。ホモマウスは生存性、妊性あり。ライン177 (B6背景) (RBRC02374) 、ライン32 (混合背景) (RBRC02375) 、ライン142 (混合背景) (RBRC02376) 、ライン177 (混合背景) (RBRC02377) 。,
Cav3 (caveolin 3) 遺伝子のノックアウトマウス。ホモマウスは生存性、妊性あり。ライン177 (B6背景) (RBRC02374) 、ライン32 (混合背景) (RBRC02375) 、ライン142 (混合背景) (RBRC02376) 、ライン177 (混合背景) (RBRC02377) 。
B6;129S4-Cav3<tm1Ncnp>/32
B6;129S4-Cav3<tm1Ncnp>/32
笹岡 俊邦
Developed by Toshikuni Sasaoka, National Institutes of Natural Sciences (National Institute of Neuroscience, National Center of Neurology and Psychiatry).
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
D (more than 6 months)
条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Hum. Mol. Genet., 9, 3047-3054 (2000).<br>利用者は、研究成果の公表にあたって、笹岡俊邦博士へ謝辞の表明を必要とする。利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、寄託者と別途協議を行う。
Homozygote x Heterozygote [or Crossing to C57BL/6JJcl]
true
基礎生物学研究所（国立精神・神経医療研究センター神経研究所）・笹岡俊邦。
RBRC02375
J1 [129S4/SvJae]
Cav3 (Caveolin 3) gene knockout mice. Cav3 is a muscle-specific form of the caveolin family proteins, which are small molecular weight proteins shown to be associated with the caveolar plasma membrane. Homozygous mutant mice show mid myopathic changes in muscle from 8 weeks ages. Viable and fertile. Line 177 (C57BL/6 background) (RBRC02374), Line 32 (mixed background) (RBRC02375), Line 142 (mixed background), Line 177 (mixed background) (RBRC02377).
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hum. Mol. Genet., 9, 3047-3054 (2000).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.