D(6か月以上)
Heterozygote x Wild-type
Heterozygote x Wild-type
No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
条件を付加しない。
true
FVB.Cg-Atp2b2<tm1Ges>
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://www.imperial.ac.uk/people/t.knopfel" target="_blank">Contact Information</A>
FVB.Cg-Atp2b2<tm1Ges>
PMCA2遺伝子のノックアウトマウス。ホモマウスは運動失調。
<a href='https://brc.riken.jp/mus/pcr04709'>Genotyping protocol -PCR-</a>
Thomas Knoepfel
Thomas Knoepfel
RBRC04709
University of Cincinnati Colllege of Medicine・Dr Gary Shullにより開発。理化学研究所脳科学総合研究センター・Dr. Thomas Knoepfelより寄託。
PMCA2 knockout mouse. Deficient in the plasma membrane Ca2+ ATPase variant 2, PMCA2. Homozygous mutant mice are viable but show motor deficits, deficits in hearing and disturbance of the sense of balance.
D (more than 6 months)
mouse PMCA2 genomic DNA, E. coli neomycin resistance gene, mouse phosphoglycerate kinase promoter (PGK promoter)
Developed Dr. Gary Shull, University of Cincinnati College of Medicine. Deposited by Dr. Thomas Knoepfel, RIKEN Brain Science Institute.