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    <dc:description xml:lang="ja">Dnd1遺伝子を含むBACコンストラクト (RP24-387I16) のトランスジーンを導入したトランスジェニックマウス。Dnd1遺伝子のC側末端に3xFLAGを持つ。Dnd1遺伝子は生殖細胞特異的に発現するRNA結合タンパク質であり、自然突然変異Terの原因遺伝子である、Ter変異のホモマウスについては、129系統では高頻度で精巣テラトーマを発症するが、他の系統においては、始源生殖細胞が死滅し不妊となることが知られている。精巣テラトーマ発症機構の解明、生殖細胞形成機構の解明に有用である。</dc:description>
    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
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    <skos:altLabel xml:lang="en">BAC-Dnd1-FLAG #1</skos:altLabel>
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    <ns0:brs_depositor xml:lang="ja">鈴木　敦</ns0:brs_depositor>
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    <dcterms:identifier>RBRC04771</dcterms:identifier>
    <ns1:strainDevelopment xml:lang="ja">Developed by Dr. Atsushi Suzuki, Interdisciplinary Research Center, Yokohama National University in 2010. B6C3F1受精卵にBACトランスジーンを挿入して作出。ICR (MCH) に戻し交配を行う。</ns1:strainDevelopment>
    <ns5:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;利用者は事前に寄託者と国立遺伝学研究所・相賀裕美子教授に連絡をとり、提供承諾を得る。また、寄託後2年間について寄託者に連絡をし、共同研究の要否に関する確認を取り、共同研究が必要な場合には共著とする。</ns5:termsAndConditions>
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    <ns1:strainDevelopment xml:lang="en">Developed by Dr. Atsushi Suzuki, Interdisciplinary Research Center, Yokohama National University in 2010.</ns1:strainDevelopment>
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    <ns5:addinfo>&lt;a href='https://brc.riken.jp/mus/pcr04771'&gt;Genotyping protocol -PCR-&lt;/a&gt;</ns5:addinfo>
    <ns0:brs_depositor xml:lang="en">Atsushi SUZUKI</ns0:brs_depositor>
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    <ns1:colonyMaintenance xml:lang="ja">Carrier x Noncarrier [or Crossing to Jcl:MCH(ICR)]</ns1:colonyMaintenance>
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    <ns5:termsAndConditions xml:lang="en">The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from DEPOSITOR and Prof. Yumiko Saga, National Institute of Genetics.  The RECIPIENT must contact the DEPOSITOR and notify him/her a content of research.  If the DEPOSITOR judges that the research should be a collaborative work, then the RECIPIENT must include the DEPOSITOR and /or the DEVELOPER's names as co-authors.</ns5:termsAndConditions>
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    <ns1:strainDevelopment xml:lang="ja">Developed by Dr. Atsushi Suzuki, Interdisciplinary Research Center, Yokohama National University in 2010.B6C3F1受精卵にBACトランスジーンを挿入して作出。ICR (MCH) に戻し交配を行う。</ns1:strainDevelopment>
    <ns5:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns5:addinfo>
    <ns1:expectedDelivery xml:lang="ja">C（3〜6か月）</ns1:expectedDelivery>
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    <ns1:donorDNA>Mouse BAC(RP24-387I16), yeast FRT (flipase recombination target) site, FLAG epitope tag sequence (synthetic DNA)</ns1:donorDNA>
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