IFN gamma knockout mice. Homozygous mutant mice show increased susceptibility to infection.
1997年 東京大学医科学研究所 岩倉洋一郎先生らにより開発。 A3-1 ES細胞由来、BALB/cAに8世代戻し交配 (兄妹交配29代) (BRC寄託時)。 129X1/SvJ (A3-1)
E. coli lacZ gene, SV40 PolyA signal, herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli Neomycin resistance gene, mouse Ifng genomic DNA
Fluorescent Proteins/lacZ System
Yoichiro IWAKURA
C.129X1-Ifng<tm1Yiw>
C(3〜6か月)
IFN gamma 遺伝子欠損マウス。lacZ遺伝子が挿入されている。細胞内寄生性細菌等に対して易感染性。
BALB-Ifng KO
条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。J. Immunol., 159, 1418-1428 (1997).<br>利用者は事前に岩倉洋一郎教授(iwakura@rs.tus.ac.jp;東京理科大学生命医科学研究所)にコンタクトをとり、利用の承諾を得ること。
RBRC04903
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 159, 1418-1428 (1997).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
BALB/cAJcl
Developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1997. The mice were backcrossed to BALB/c for at least 8 times.
Immunology and Inflammation Research
<a href='https://brc.riken.jp/mus/pcr04903'>Genotyping protocol -PCR-</a>
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
C (3-6 months)
C;129X1-Ifng<tm1Yiw>
C;129X1-Ifng<tm1Yiw>
1997年 東京大学医科学研究所 岩倉洋一郎先生らにより開発。A3-1 ES細胞由来、BALB/cAに8世代戻し交配 (兄妹交配29代) (BRC寄託時)。129X1/SvJ (A3-1)
true
岩倉 洋一郎