C3.129X1-Ifng<tm1Yiw> C3.129X1-Ifng<tm1Yiw> In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J Immunol., 159(3):1418-1428 (1997).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. 1997年 東京大学医科学研究所 岩倉洋一郎先生らにより開発。A3-1 ES細胞由来。C3H/HeNに8世代戻し交配 (兄妹交配4代) (BRC寄託時)。129X1/SvJ (A3-1) C3H/HeNSlc (C3H/HeNJclが混ざっている可能性有) Immunology and Inflammation Research D (more than 6 months) RBRC04923 Yoichiro IWAKURA Developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1997. The mice were backcrossed to C3H for at least 8 times by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo. C3-Ifng KO Neomycin resistance gene, lacZ gene (E. coli), PolyA signal (SV40), MC1 promoter (HSV) IFN gamma knockout mice. Homozygous mutant mice show increased susceptibility to infection. Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> IFN gamma遺伝子欠損マウス。lacZ遺伝子が挿入されている。細胞内寄生性細菌等に対して易感染性。 true 1997年 東京大学医科学研究所 岩倉洋一郎先生らにより開発。 A3-1 ES細胞由来。 C3H/HeNに8世代戻し交配 (兄妹交配4代) (BRC寄託時)。 129X1/SvJ (A3-1) 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。J Immunol., 159(3):1418-1428 (1997).<br>利用者は事前に岩倉洋一郎教授(iwakura@rs.tus.ac.jp;東京理科大学生命医科学研究所)にコンタクトをとり、利用の承諾を得ること。 D(6か月以上) 岩倉 洋一郎