C(3〜6か月)
Sox1 cre knock-in mice. knocked into the Sox1 gene. No obvious defect at the heterozygous state which is used for the conditional KO or cell tracing purposes.
TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Heterozygote X Wild-type [C57BL/6NJcl]
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
RBRC05065
B6-Sox1/cre KI
B6-Sox1/cre KI
Cre recombinase was inserted into the ATG codon start site if Sox1 by in-frame. PGK-neo cassette was removed by Flp recombinase expression.
Cre/loxP system
Phage P1 cre recombinase, yeast FRT (flippase recombination target) site, mouse Sox1 genomic DNA
FLP/frt system
B6.B6CB-Sox1<tm1(cre)Take>
B6.B6CB-Sox1<tm1(cre)Take>
条件を付加する。<br>(1) 当該マウスを用いる論文発表に際しては Accession No. CDB0525K、その WEB サイト(http://www2.clst.riken.jp/arg/mutant%20mice%20list.htmlとともに当該マウスを記載すること。(2) 当該マウスを用いる論文発表に際しては、その由来として第一報論文(Cell, 129, 1377-1388 (2007).)を引用すること。
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0525K, and Web Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) and the BIOLOGICAL RESOURCE is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Cell, 129, 1377-1388 (2007).)
true
RIKEN CDB
RIKEN CDB
<a href='https://brc.riken.jp/mus/pcr05065'>Genotyping protocol -PCR-</a>
C (3-6 months)