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    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_5"/>
    <ns6:brs_depositor xml:lang="en">Fugaku AOKI</ns6:brs_depositor>
    <ns1:expectedDelivery xml:lang="ja">C（3〜6か月）</ns1:expectedDelivery>
    <dc:description xml:lang="en">Flag-macroH2A1.2 (H2afy) transgenic mice.</dc:description>
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    </ns6:brs_hasGenomicFeature>
    <ns1:colonyMaintenance xml:lang="en">Carrier x Noncarrier</ns1:colonyMaintenance>
    <ns9:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;CAGGS MTA (&lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/CAGGS_MTA.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns4:addinfo>
    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainType_24"/>
    <skos:altLabel xml:lang="ja">B6-Flag/mH2A1.2 Tg</skos:altLabel>
    <skos:altLabel xml:lang="en">B6-Flag/mH2A1.2 Tg</skos:altLabel>
    <ns1:references rdf:parseType="Resource">
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    <ns6:brs_depositedBy rdf:parseType="Resource">
    </ns6:brs_depositedBy>
    <ns4:termsAndConditions xml:lang="ja">条件を付加しない。</ns4:termsAndConditions>
    <rdfs:seeAlso rdf:resource="http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC05075"/>
    <rdfs:subClassOf rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/Strain"/>
    <ns1:colonyMaintenance xml:lang="ja">戻し交配系統名 (ブリーダー名) : C57BL/6 (日本SLC)</ns1:colonyMaintenance>
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    </ns6:brs_depositedBy>
    <ns4:resourceTypeLink rdf:resource="http://metadb.riken.jp/terms/xsearch#resource_type_transgene"/>
    <ns6:brs_hasAllele rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/brc_allele1160"/>
    <dcterms:references rdf:resource="http://identifiers.org/pubmed/20943707"/>
    <ns1:strainDevelopment xml:lang="en">Developed by Nashun Buhe, Masashi Yukawa and Fugaku Aoki, Graduate School of Frontier Sciences, The University of Tokyo in 2009. Transgene was injected into the pronuclei of B6D2F1 fertilized eggs.</ns1:strainDevelopment>
    <ns1:isRecombinant rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean"
    >true</ns1:isRecombinant>
    <ns4:termsAndConditions xml:lang="en">No specific terms and conditions.    (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)</ns4:termsAndConditions>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <ns6:brs_depositor xml:lang="ja">青木　不学</ns6:brs_depositor>
    <dcterms:identifier>RBRC05075</dcterms:identifier>
    <ns5:organism rdf:parseType="Resource">
    </ns5:organism>
    <ns4:addinfo>&lt;A HREF="https://mus.brc.riken.jp/en/mouse_of_month/oct_2011_mm" target="_blank"&gt;Mouse of the Month Oct 2011&lt;/A&gt;</ns4:addinfo>
    <ns5:organism rdf:parseType="Resource">
    </ns5:organism>
    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
    <ns6:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_3"/>
    <ns1:references rdf:parseType="Resource">
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    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_6"/>
    <ns1:colonyMaintenance xml:lang="ja">戻し交配 系統名 (ブリーダー名) : C57BL/6 (日本SLC)</ns1:colonyMaintenance>
    <dc:description xml:lang="ja">macroH2A1.2トランスジェニックマウス。macroH2A1.2 (H2afy) はヒストンH2Aの変異体であり、不活性X染色体に多く局在する。遺伝子発現に抑制的に働くと考えられている。</dc:description>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <ns1:strainDevelopment xml:lang="ja">東京大学大学院新領域創成科学研究科 青木不学先生、那順布和先生、湯川将之先生 (2009) B6D2F1の受精卵にマイクロインジェクションして作成。C57BL/6と交配を行い維持。</ns1:strainDevelopment>
    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/straintype_2"/>
    <ns1:strainDevelopment xml:lang="ja">東京大学大学院新領域創成科学研究科 青木不学先生、那順布和先生、湯川将之先生 (2009)B6D2F1の受精卵にマイクロインジェクションして作成。C57BL/6と交配を行い維持。</ns1:strainDevelopment>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
    </ns6:brs_hasGenomicFeature>
    <rdfs:label>B6;B6D2-Tg(CAG-flag-macroH2A1.2)</rdfs:label>
    <rdfs:label xml:lang="en">B6;B6D2-Tg(CAG-flag-macroH2A1.2)</rdfs:label>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
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    <ns7:SIO_001279 rdf:parseType="Resource">
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    </ns6:brs_hasGenomicFeature>
    <ns7:SIO_001279 rdf:parseType="Resource">
    </ns7:SIO_001279>
    <ns1:donorDNA>Flag-tag cDNA, Mouse Histone macroH2A1.2 (H2afy) gene cDNA, CMV IE enhancer, Chicken CAG prompter (beta-actin promoter + globin intron), Rabbit beta-globin PolyA signal</ns1:donorDNA>
    <ns11:citesAsAuthority rdf:resource="http://rdf.ncbi.nlm.nih.gov/pubmed/20943707"/>
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