B4galt1 knockout mice. Homozygous mutant mice are embryonic lethal.
条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。EMBO J., 16, 1850-1857 (1997).<br>利用者は事前に岩倉洋一郎教授(iwakura@rs.tus.ac.jp;東京理科大学生命医科学研究所)にコンタクトをとり、利用の承諾を得ること。
Neomycin resistance gene (E. coli), Phosphoglycerate kinase (PGK) promoter (mouse)
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J., 16, 1850-1857 (1997).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
Developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1997. The mice were backcrossed to C57BL/6 for at least 8 times.
B6.129-B4galt1<tm1Yiw>
B6.129-B4galt1<tm1Yiw>
岩倉 洋一郎
D (more than 6 months)
C57BL/6JJmsSlc
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
true
D(6か月以上)
RBRC05139
beta1, 4-ガラクトース転移酵素I型遺伝子欠損マウス。ホモ欠損個体は胎生致死。
1997年 東京大学医科学研究所 岩倉洋一郎先生らにより開発。R1 ES細胞由来。C57BL/6Jに8世代戻し交配 (BRC寄託時)。(129X1/SvJ × 129S1/Sv) F1-Kitl<+> (R1)
1997年 東京大学医科学研究所 岩倉洋一郎先生らにより開発。 R1 ES細胞由来。C57BL/6Jに8世代戻し交配 (BRC寄託時)。 (129X1/SvJ × 129S1/Sv) F1-Kitl<+> (R1)
Yoichiro IWAKURA
B6-B4galt1 KO