C(3〜6か月)
<A HREF="https://mus.brc.riken.jp/en/mouse_of_month/oct_2013_mm" target="_blank">Mouse of the Month Oct 2013</A>
RIKEN CDB
RIKEN CDB
RBRC05281
LtbR (Acc. No. CDB0531K)
徳島大学分子酵素学研究センター 松本 満先生。
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
LtbR (Acc. No. CDB0531K)
LtbR (Acc. No. CDB0531K)
Heterozygote x Wild-type [C57BL/6N]
Developed by Mitsuru Matsumoto, Institute for Enzyme Research, The University of Tokushima.
Lymphotoxin B receptor knockout mice. Homozygous mutant miceexhibit accumulation of lymphoid cell aggregates (B220+, CD4+, and CD8+ lymphocytes) in the liver and lung.
C (3-6 months)
B6.Cg-Ltbr<tm1Mmat>/Rbrc
<a href='https://brc.riken.jp/mus/pcr05281'>Genotyping protocol -PCR-</a>
true
(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Mitsuru Matsumoto, The University of Tokushima, E-mail: mitsuru@ier.tokushima-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0531K and Web. Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Immunol. 2011 186(9):5047-57.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
phage P1 lox71, E. coli lacZ, polyA, yeast FRT (flipase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse PGK3’end, phage P1 loxP site, rabbit beta-globin 3’end, mouse LtbR genomic DNA
条件を付加する。<br>(1) 分与希望者は事前に開発者 (徳島大学、松本 満博士, E-mail: mitsuru@ier.tokushima-u.ac.jp) に連絡をとり、分与に関して許可を得ること。(2)当該マウスを用いる論文発表に際してはAcc.No. CDB0531K、そのWEB サイト(http://www2.clst.riken.jp/arg/mutant%20mice%20list.html)とともに当該マウスを記載すること。(3)当該マウスを用いる論文発表に際しては、その由来として第一報論文J Immunol. 2011 186(9):5047-57.を引用すること。(4)発表論文を寄託者(mutant.bdr@riken.jp)に連絡すること。
Ltbr遺伝子のノックアウトマウス。