Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> C.129S4-Tecpr1<tm1> C.129S4-Tecpr1<tm1Chsa>/Rbrc 東京大学医科学研究所 小川 道永先生が作出した。Knock-out mouse was generated by using J1 ES cell.The J1 ES cell line was derived from a male aguti 129S4/Svjae embryo (blastocyst). In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Host Microbe, 9, 376-389 (2011). Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. BALB-Tecpr1 KO BALB-Tecpr1 KO 条件を付加する。<br>利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する。Cell Host Microbe, 9, 376-389 (2011).　利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、寄託者と別途協議を行う。 Tecpr1は選択的オートファジー、オートリソソームのmaturationに関与する因子である。 <a href='https://brc.riken.jp/mus/pcr05545'>Genotyping protocol -PCR-</a> 笹川　千尋 Tecpr1, tectonin beta-propeller repeat containing 1 gene knockout mice. A neomycin selection cassette was inserted into the exon 2-6 of the Tecpr1 gene. true BALB/cAJclコンジェニック系統。BALB/cAJclに10世代戻し交配を行う。その後、兄妹交配にて維持。 交配により Y 染色体は BALB/cAJcl 置換済み。 Klebsiella pneumoniae neomycin resistance gene, mouse Tecpr1 genomic DNA BALB-Tecpr1 KO, C.129S4-Tecpr1<tm1> BALB-Tecpr1 KO, C.129S4-Tecpr1<tm1> Heterozygote x Wild-type [BALB/cAJcl] Developed by Michinaga Ogawa, The Institute of Medical Science, The University of Tokyo. Knockout mice were generated by using J1 ES cells (129S4/SvJae derived). The mutant mice were backcrossed to BALB/cAJcl. Michinaga OGAWA C (3-6 months) 東京大学医科学研究所 小川 道永先生が作出した。 Knock-out mouse was generated by using J1 ES cell. The J1 ES cell line was derived from a male aguti 129S4/Svjae embryo (blastocyst). RBRC05545 Chihiro SASAKAWA BALB/cAJclコンジェニック系統。BALB/cAJclに10世代戻し交配を行う。その後、兄妹交配にて維持。交配により Y 染色体は BALB/cAJcl 置換済み。 C（3〜6か月） 小川　道永