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    <ns1:strainDevelopment xml:lang="ja">東京大学 谷口研, 渋江 司先生 (2003年)E14-1 ES cell</ns1:strainDevelopment>
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    <dc:description xml:lang="ja">NoxaはBcl-2ファミリー分子の一つで、P53によって発現誘導されるBH3-only因子である。Noxa欠損細胞 (MEF) はDNAダメージ応答における癌遺伝子依存的アポトーシスに対して耐性である。</dc:description>
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    <ns5:termsAndConditions xml:lang="ja">条件を付加する。利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。&lt;br&gt;研究成果の公表にあたって謝辞の表明を必要とする。&lt;br&gt;利用者は使用目的を寄託者に通知し、この目的の範囲内でのみ使用し、結果を通知する。</ns5:termsAndConditions>
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    <ns1:colonyMaintenance xml:lang="ja">C57BL/6Jとの戻し交配は15世代以上。Y染色体については不明。</ns1:colonyMaintenance>
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    <ns1:strainDevelopment xml:lang="en">Developed by Tsukasa Shibue and Tadatsugu Taniguchi, Graduate School of Medicine, University of Tokyo in 2003. E14.1 ES cell derived. The mutant mice were backcrossed to C57BL/6J.</ns1:strainDevelopment>
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