D (more than 6 months) true Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://egr.biken.osaka-u.ac.jp/achievement/bio_resources" target="_blank">Lab HP</A> D(6か月以上) 伊川 正人 Testis specific Calr3 gene transgenic mice. Endogenous Calr3 expression was absent. Tg males are viable. Developmental Biology Research The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 286, 5639-5646 (2011).RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (https://www.ccb.osaka-u.ac.jp/en/). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. KO : Homozygote x Homozygote ; Tg : Carrier x Carrier [or Crossing to Jcl:B6D2F1] KO : Homozygote x Homozygote ; Tg : Carrier x Carrier [or Crossing to Jcl:B6D2F1] Masahito IKAWA 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。J. Biol. Chem., 286, 5639-5646 (2011).<br>非営利機関が非営利目的の教育・研究用に用いる場合以外は、大阪大学と別途MTAを締結すること(https://www.ccb.osaka-u.ac.jp/en/)。5年経過後も使用を希望するときは改めて寄託者から承諾を得るものとする。 大阪大学微生物病研究所 伊川 正人先生 (2006) B6D2-Calr3<tm1Osb> Tg(Calr3-Calr3)Osb B6D2-Calr3<tm1Osb> Tg(Calr3-Calr3)Osb 精巣特異的にCalr3遺伝子を発現するトランスジェニックマウス。内在性Calr3遺伝子を欠損する。 KOマウスの表現型 (雄性不妊) を回復させることが可能な量のCalr3を精巣に発現している。 RBRC05729 mouse Calr3 genomic DNA, E. coli Neomycin resistance gene, mouse Calr3 cDNA, rabbit globin polyA signal Developed by Masato Ikawa, Research Institute for Microbial Diseases, Osaka University in 2006. Calr3 Tg Calr3 Tg