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    <dcterms:references rdf:resource="http://identifiers.org/pubmed/10804175"/>
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    <ns1:expectedDelivery xml:lang="ja">D（6か月以上）</ns1:expectedDelivery>
    <ns10:citesAsAuthority rdf:resource="http://rdf.ncbi.nlm.nih.gov/pubmed/10205173"/>
    <rdfs:label xml:lang="en">ICR;129-Hes5&lt;tm1Fgu&gt;</rdfs:label>
    <rdfs:label>ICR;129-Hes5&lt;tm1Fgu&gt;</rdfs:label>
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    <ns4:termsAndConditions xml:lang="en">In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J. 1999 18(8):2196-207.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.  The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama  (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).</ns4:termsAndConditions>
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    <ns1:ESCellLine>R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl&lt;+&gt;]</ns1:ESCellLine>
    <dc:description xml:lang="ja">Hes5遺伝子のノックアウトマウス。</dc:description>
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    </ns1:references>
    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns4:addinfo>
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    <ns6:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_2"/>
    <rdfs:seeAlso rdf:resource="http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC05981"/>
    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_3"/>
    <ns7:SIO_001279 rdf:parseType="Resource">
    </ns7:SIO_001279>
    <ns6:brs_depositor xml:lang="en">Ryuichiro KAGEYAMA</ns6:brs_depositor>
    <ns7:SIO_001279 rdf:parseType="Resource">
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    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/straintype_14"/>
    <ns6:brs_hasGenomicFeature rdf:parseType="Resource">
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    <skos:altLabel xml:lang="ja">Hes5 KO (Neo)  ; Hes5 KO</skos:altLabel>
    <skos:altLabel xml:lang="en">Hes5 KO (Neo)  ; Hes5 KO</skos:altLabel>
    <ns1:strainDevelopment xml:lang="ja">京都大学大学院医学研究科/IGBMC・影山龍一郎（1996）。R1 ES細胞由来を用いて作出。ICRと交配。</ns1:strainDevelopment>
    <ns6:brs_depositor xml:lang="ja">影山龍一郎</ns6:brs_depositor>
    <ns6:brs_depositor xml:lang="en">Itaru IMAYOSHI</ns6:brs_depositor>
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    <ns1:expectedDelivery xml:lang="en">D (more than 6 months)</ns1:expectedDelivery>
    <dcterms:references rdf:resource="http://identifiers.org/pubmed/10205173"/>
    <ns1:donorDNA>mouse phosphoglycerate kinase promoter (PGK promoter), Neo (E. coli), mouse Hes5 genomic DNA</ns1:donorDNA>
    <ns6:brs_depositor xml:lang="ja">今吉　格</ns6:brs_depositor>
    <ns1:strainDevelopment xml:lang="en">Developed by Ryoichiro Kageyama, Kyoto University/IGBMC in 1996.  R1 ES cells were used.  The mutant mice were crossed to ICR.</ns1:strainDevelopment>
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    <ns10:citesAsAuthority rdf:resource="http://rdf.ncbi.nlm.nih.gov/pubmed/10804175"/>
    <dcterms:identifier>RBRC05981</dcterms:identifier>
    <ns4:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;研究成果の公表にあたって寄託者の指定する文献を引用する。EMBO J. 1999 18(8):2196-207.&lt;br&gt;研究成果の公表にあたって謝辞の表明を必要とする。&lt;br&gt;学術機関の学術研究に限る。分与希望者は事前に 影山龍一郎 (E-mail: rkageyam@virus.kyoto-u.ac.jp) に連絡をとり、分与に関して許可を得ること。（提供承諾書（書式6）の提出は不要）。</ns4:termsAndConditions>
    <dc:description xml:lang="en">Hes5 gene knockout mice.  724 bp including the coding region from Met1 to Ala76 (bHLH domain) was replaced with a PGK-neo cassette.</dc:description>
    <ns1:colonyMaintenance xml:lang="ja">Heterozygote x Wild-type [or Crossing to Slc:ICR]</ns1:colonyMaintenance>
    <ns1:colonyMaintenance xml:lang="en">Heterozygote x Wild-type [or Crossing to Slc:ICR]</ns1:colonyMaintenance>
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