TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev. 2001 15(20):2642-7.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). ICR.Cg-Hes7<tm1Kag> ICR.Cg-Hes7<tm1Kag> Hes7遺伝子のノックアウトマウス。ほとんどのcording領域がIRES-lacZ-PGK-neoカセットで置換されている。ほとんどのホモマウスは生後数時間で死亡。 RBRC05983 Heterozygote x Wild-type [or Crossing to Slc:ICR] Heterozygote x Wild-type [or Crossing to Slc:ICR] Most of the coding region was replaced with a IRES-lacZ-PGK-neo cassette. Most homozygous mutant mice die within a few hours of birth. 影山龍一郎 D (more than 6 months) Ryuichiro KAGEYAMA Itaru IMAYOSHI D（6か月以上） 京都大学ウィルス研究所・影山龍一郎（2001）。TT2 ES細胞由来を用いて作出。ICRと交配。 今吉　格 Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2001. TT2 ES cells were used. The mutant mice were crossed to ICR. 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Genes Dev. 2001 15(20):2642-7.<br>研究成果の公表にあたって謝辞の表明を必要とする。<br>学術機関の学術研究に限る。分与希望者は事前に 影山龍一郎 (E-mail: rkageyam@virus.kyoto-u.ac.jp) に連絡をとり、分与に関して許可を得ること。（提供承諾書（書式6）の提出は不要）。 Fluorescent Proteins/lacZ System EMCV (Encephalomyocarditis virus) internal ribosomal entry site (IRES), beta galactosidase (E. coli), mouse phosphoglycerate kinase promoter (PGK promoter), Neo (E. coli), mouse Hes7 genomic DNA Hes7 KO ; Hes7 KO/lacZ Hes7 KO ; Hes7 KO/lacZ true