橋本 有弘
C（3〜6か月）
mouse Myod1 genomic DNA, Klebsiella pneumoniae neomycin resistance gene, mouse phosphoglycerate kinase promoter (PGK promoter)
MyoD-KO, D2-Myod1 KO
MyoD-KO, D2-Myod1 KO
<a href='https://brc.riken.jp/mus/pcr06190'>Genotyping protocol -PCR-</a>
Naohiro HASHIMOTO
MyoD1遺伝子のノックアウトマウス。BALB/cなどにコンジェニックすると、表現型が一部異なってくるとされている。,
Homozygote x Homozygote
Homozygote x Homozygote
MyoD1 gene knockout mice. The Myod1 promoter, exon 1 and half of intron 1 were replaced with a a neomycin cassette.
Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>
D2;129-Myod1<tm1Jae>
D2;129-Myod1<tm1Jae>
true
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 71, 383-390 (1992).
Developed by Rudolf Jaenisch, Whitehead Institute and Department of Biology Massachusetts Institute of Technology Cambridge. J1 ES cells were used. The mutant mice were maintained by Naohiro Hashimoto, National Center for Geriatrics and Gerontology. 129 and DBA/2 mixed background.
条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Cell, 71, 383-390 (1992).
MyoD1遺伝子のノックアウトマウス。BALB/cなどにコンジェニックすると、表現型が一部異なってくるとされている。
RBRC06190
C (3-6 months)
Mouse Models for Human Disease
Whitehead Institute and Department of Biology Massachusetts Institute of Technology Cambridge・Rudolf Jaenischらにより開発。長寿医療研究センター研究所・橋本有弘先生により維持された。129とDBA/2混合背景。