R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] 理化学研究所・免疫アレルギー科学総合研究センター・深田俊幸先生(2013)。R1 ES細胞由来。C57BL/6マウスに戻し交配(9世代以上)。 Developmental Biology Research Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLOS Genetics 12(10): e1006349, (2016). B6;129-Slc39a7<tm1.1Tfk> ZIP7 KO, B6-Slc39a7 floxed, B6;129-Slc39a7<tm1> ZIP7 KO, B6-Slc39a7 floxed, B6;129-Slc39a7<tm1> 小安 重夫 <a href='https://brc.riken.jp/mus/pcr06225'>Genotyping protocol -PCR-</a> true Cre/loxP system 深田 俊幸 Zip7 (Slc39a7) 遺伝子のfloxedマウス。エクソン5と6がloxPで挟まれている。ホモマウスは外見上、特に異常は認められない。 ZIP7 KO, B6-Slc39a7 floxed ZIP7 KO, B6-Slc39a7 floxed Toshiyuki FUKADA C (3-6 months) Homozygote x Homozygote [or Crossing to C57BL/6JJcl] Homozygote x Homozygote [or Crossing to C57BL/6JJcl] B6;129-Slc39a7<tm1> Shigeo KOYASU Enterobacteria phage P1 loxP sites, mouse Slc39a13 genomic DNA Zip7 (Slc39a7) gene floxed mice. Exons 5 and 6 were flanked by loxP sites. C(3〜6か月) RBRC06225 条件を付加する。利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。PLOS Genetics 12(10): e1006349, (2016). Developed by Toshiyuki Fukuda, RIKEN Center for Allergy and Immunology in 2013. R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> were used for the generation of floxed mice. The mutant mice were crossed to C57BL/6J over 9 times. Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol>