D1Mit501-Fcgr2b: Homozygote x Homozygote; Fcgr2b: Homozygote x Homozygote [or Crossing to C57BL/6NCrlCrlj] D1Mit501-Fcgr2b: Homozygote x Homozygote; Fcgr2b: Homozygote x Homozygote [or Crossing to C57BL/6NCrlCrlj] B6.129-(D1Mit501-Fcgr2b) Fcgr2b<tm1Ttk>/Hros B6.129-(D1Mit501-Fcgr2b) Fcgr2b<tm1Ttk>/Hros 廣瀬　幸子 C（3〜6か月） true mouse Fcgr2b genomic DNA, E. coli Neomycin resistance gene <a href='https://brc.riken.jp/mus/pcr06308'>Genotyping protocol -PCR-</a> Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> Developed by Sachiko Hirose, Juntendo University School of Medicine. 順天堂大学大学院医学研究科・広瀬幸子先生。129系統由来ES細胞を用いてジーンターゲティングされたFcgr2b KOマウス（東北大学加齢医学研究所・高井俊行先生）を基に育成。 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Arthritis Rheum., 63, 2930-2938 (2011). Immunology and Inflammation Research Fcgr2b gene knockout mice. This strain carries a chromosomal region of D1Mit501 to Fcgr2b derived from 129 ES cells and Fcgr2b knockout allele. Homozygous mutant mice show no obvious abnormality. RBRC06308 129系統由来ES細胞を用いてFcγRIIB遺伝子を欠損し、D1Mit501からFcγRIIB遺伝子までの領域が129に由来するB6コンジェニック系統 (通称KO2系統) 。病的所見は特に認められない。, KO2, B6-D1Mit501-Fcgr2b/Fcgr2b KO KO2, B6-D1Mit501-Fcgr2b/Fcgr2b KO 129系統由来ES細胞を用いてFcγRIIB遺伝子を欠損し、D1Mit501からFcγRIIB遺伝子までの領域が129に由来するB6コンジェニック系統 (通称KO2系統) 。病的所見は特に認められない。 In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Arthritis Rheum., 63, 2930-2938 (2011). Sachiko HIROSE C (3-6 months)