Chrono KO Chrono KO Chrono KO, Ciart knockout Chrono KO, Ciart knockout <a href='https://brc.riken.jp/mus/pcr09305'>Genotyping protocol -PCR-</a> C (3-6 months) RBRC09305 時計遺伝子、BMAL1/CLOCKによるE-box配列での転写活性を抑制する機能を持つ。Chrono KOの行動リズムはWT (野生型) に比べて延長する。 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>利用者は別途、TIGM指定のMTAを提出する。利用が学術の学術研究に限る。 C（3〜6か月） Toru TAKUMI Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li><A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/TIGM_MTA.docx">TIGM_MTA</A></li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> 内匠　透 The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT is requested to execute a MTA specified by TIGM. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. Ciart knockout C57BL/6-Ciart<GT(IST11761C7)Tigm>/Taku true Fluorescent Proteins/lacZ System retrovirus LTR (viral long terminal repeat), SA (splice acceptor), Bgeo (E. coli neo, E. coli lacZ), SV40 polyA, mouse Ciart genomic DNA