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    <dc:description xml:lang="en">A chemokine receptor, XCR1, is a receptor for XCL1 and expressed dominantly in one dendritic cell subset. XCR1-venus mice were generated by knocking the gene encoding a fluorescence protein, venus (derived from Dr. Atsushi Miyawaki at BRI) into the murine XCR1 gene locus. In XCR1-venus mice, XCR1-expressing cells can be detected by venus expression.</dc:description>
    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Approval form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEVELOPER of the Venus using Approval form (&lt;a HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/Form_V.docx"&gt;Form V (English)&lt;/a&gt;) (Lab Contact: Laboratory for Cell Function Dynamics, RIKEN CBS: mta-cfds@ml.riken.jp).&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns4:addinfo>
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    <dc:description xml:lang="ja">ケモカイン受容体XCR1は、ケモカインXCL1の受容体であり、主として樹状細胞の一つのサブセットに高い特異性をもって発現している。本マウスは、XCR1遺伝子座に蛍光タンパク質venus遺伝子をノックインしたマウスであり、Venusの発現にて、XCR1陽性細胞を同定できる。A chemokine receptor, XCR1, is a receptor for XCL1 and expressed dominantly in one dendritic cell subset. XCR1-venus mice were generated by knocking the gene encoding a fluorescence protein, venus (derived from Dr. Atsushi Miyawaki at BRI) into the murine XCR1 gene locus. In XCR1-venus mice, XCR1-expressing cells can be detected by venus expression.</dc:description>
    <ns1:donorDNA>Aequorea coerulescens mutant GFP (venus) cDNA, Bos taurus bGHpolyA, Bacteriophage P1 loxP sites, Saccharomyces cerevisiae FRT sites, herpes simplex virus thymidine kinase promoter (HSV tk promoter), Escherichia coli Neomycin resistant gene, HSV TK polyA signal, mouse Xcr1 genomic DNA</ns1:donorDNA>
    <ns4:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;1. 利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。　&lt;br&gt;2. 研究成果の公表にあたって寄託者の指定する文献を引用する　J. Immunol., 190, 6071-6082 (2013). &lt;br&gt;3. 学術機関の学術研究に限る。営利機関の利用希望者は、事前に利用条件等につき寄託者と合意し、提供承諾を得ること。　&lt;br&gt;4. 利用者はApproval form (form V)を用いて、事前にVenusの開発者の許可を得る。（連絡先：Laboratory for Cell Function Dynamics, RIKEN CBS: mta-cfds@ml.riken.jp）</ns4:termsAndConditions>
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    <dc:description xml:lang="ja">ケモカイン受容体XCR1は、ケモカインXCL1の受容体であり、主として樹状細胞の一つのサブセットに高い特異性をもって発現している。本マウスは、XCR1遺伝子座に蛍光タンパク質venus遺伝子をノックインしたマウスであり、Venusの発現にて、XCR1陽性細胞を同定できる。,A chemokine receptor, XCR1, is a receptor for XCL1 and expressed dominantly in one dendritic cell subset. XCR1-venus mice were generated by knocking the gene encoding a fluorescence protein, venus (derived from Dr. Atsushi Miyawaki at BRI) into the murine XCR1 gene locus. In XCR1-venus mice, XCR1-expressing cells can be detected by venus expression.</dc:description>
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    <ns1:ESCellLine>Bruce 4 [B6.Cg-Thy1&lt;a&gt;]</ns1:ESCellLine>
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    <ns1:strainDevelopment xml:lang="ja">改正恒康先生（理化学研究所　統合生命医科学研究センター　炎症制御研究チーム　客員主管研究員）が理化学研究所　免疫・アレルギー科学総合研究センターにて2008年頃作製した。C57BL/6 コンジェニック系統。C57BL/6JJclに11世代戻し交配を行った。Y染色体は原系統。Developed by Tsuneyasu Kaisho, Research Center for Allergy and Immunologuy, RIKEN around 2008.</ns1:strainDevelopment>
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    <rdfs:seeAlso rdf:resource="http://www2.brc.riken.jp/lab/animal/detail.php?brc_no=RBRC09486"/>
    <ns6:brs_hasAllele rdf:resource="http://metadb.riken.jp/db/mgi_rdf/MGI:5544057"/>
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    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_4"/>
    <ns6:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_5"/>
    <skos:altLabel xml:lang="en">XCR1-venus</skos:altLabel>
    <skos:altLabel xml:lang="ja">XCR1-venus</skos:altLabel>
    <ns4:addinfo>&lt;a href='https://brc.riken.jp/mus/pcr09486'&gt;Genotyping protocol -PCR-&lt;/a&gt;</ns4:addinfo>
    <ns1:expectedDelivery xml:lang="ja">C（3〜6か月）</ns1:expectedDelivery>
    <ns1:strainDevelopment xml:lang="ja">改正恒康先生（理化学研究所　統合生命医科学研究センター　炎症制御研究チーム　客員主管研究員）が理化学研究所　免疫・アレルギー科学総合研究センターにて2008年頃作製した。C57BL/6 コンジェニック系統。C57BL/6JJclに11世代戻し交配を行った。Y染色体は原系統。 Developed by Tsuneyasu Kaisho, Research Center for Allergy and Immunologuy, RIKEN around 2008.</ns1:strainDevelopment>
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    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
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    <dcterms:references rdf:resource="http://identifiers.org/pubmed/23670193"/>
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    <ns6:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_3"/>
    <ns6:brs_depositor xml:lang="ja">改正　恒康</ns6:brs_depositor>
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    <rdfs:label>B6.Cg-Xcr1&lt;tm1Ksho&gt;</rdfs:label>
    <rdfs:label xml:lang="en">B6.Cg-Xcr1&lt;tm1Ksho&gt;</rdfs:label>
    <ns4:application>Immunology and Inflammation Research</ns4:application>
    <ns10:citesAsAuthority rdf:resource="http://rdf.ncbi.nlm.nih.gov/pubmed/23670193"/>
    <ns4:application>FLP/frt system</ns4:application>
    <skos:altLabel xml:lang="en">XCR1-venus, XCR1-venus B6</skos:altLabel>
    <skos:altLabel xml:lang="ja">XCR1-venus, XCR1-venus B6</skos:altLabel>
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    >true</ns1:isRecombinant>
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    <ns4:termsAndConditions xml:lang="en">1. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form (form D). &lt;br&gt;2. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.J. Immunol., 190, 6071-6082 (2013).  &lt;br&gt;3. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit organization for a not-for-profit research.  For use of the BIOLOGICAL RESOURCE by a for-profit organization, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.&lt;br&gt;4. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEVELOPER of the Venus using Approval form (form V) (Lab Contact: Laboratory for Cell Function Dynamics, RIKEN CBS: mta-cfds@ml.riken.jp).</ns4:termsAndConditions>
    <ns4:application>Fluorescent Proteins/lacZ System</ns4:application>
    <ns1:genotypingProtocol rdf:resource="http://mus.brc.riken.jp/DataSheet/pcr09486"/>
    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainType_17"/>
    <ns6:brs_depositor xml:lang="en">Kaisho, Tsuneyasu</ns6:brs_depositor>
    <ns4:addinfo>&lt;A HREF="https://mus.brc.riken.jp/ja/mouse_of_month/jan_2016_mm" target="_blank"&gt;Mouse of the Month Jan 2016&lt;/A&gt;</ns4:addinfo>
    <ns1:strainDevelopment xml:lang="en">Developed by Tsuneyasu Kaisho, Research Center for Allergy and Immunologuy, RIKEN around 2008.</ns1:strainDevelopment>
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    <dcterms:identifier>RBRC09486</dcterms:identifier>
    <ns4:application>Cre/loxP system</ns4:application>
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