ゲノム編集技術により作製されたChd9 (chromodomain helicase DNA binding protein 9) 変異マウス。8 bpの欠損があり、本来であれば2869アミノ酸のタンパクができるところ、理論的に360アミノ酸でタンパク合成が止まる。ホモマウスは正常に生まれ、繁殖も可能。1 bp欠損の系統がRBRC9699として利用可能。 B6.Chd9 KO B6.Chd9 KO Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: CRISPR/Cas9 genome edited bioresources (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/Broad_MTA_J.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/Broad_MTA_E.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> RBRC09698 C57BL/6N-Chd9<em1Ibbr> C57BL/6N-Chd9<em1Ibbr> C（3〜6か月） Chd9 (chromodomain helicase DNA binding protein 9) mutant mice generated by the Genome editing technique (CRISPR/Cas9). This mutant contains 8 bp deletion within the Chd9 open reading frame causing a frameshift. The mutant mouse is predicted to express a 360 amino acid polypeptide, in contrast to 2869 amino acid native polypeptide. Homozygous mutants are viable and fertile. 1 bp deletion mutant of Chd9 is also available in RBRC09699. true 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。後日指定。 C (3-6 months) <a href='https://brc.riken.jp/mus/pcr09698'>Genotyping protocol -PCR-</a> In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定。 Developed by Fugaku Aoki, The University of Tokyo in 2016. Fertilized eggs derived from C57BL/6N were used. C57BL/6N background. 東京大学・青木不学(2016)により開発。C57BL/6Nの受精卵を使用。C57BL/6N背景。