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    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Approval form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns4:addinfo>
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    <ns1:donorDNA>mouse Phosphoglycerate kinase promoter (PGK promoter), E coli Neomycin resistance gene, mouse Phosphoglycerate kinase polyA signal, mouse Hist1h2aa/Hist1h2ba genomic DNA</ns1:donorDNA>
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    <ns4:addinfo>&lt;a href='https://brc.riken.jp/mus/pcr09729'&gt;Genotyping protocol -PCR-&lt;/a&gt;</ns4:addinfo>
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    <ns1:strainDevelopment xml:lang="en">Developed by Shunsuke Fujii, RIKEN in 2014. R1 ES cell line [(129X1/SvJ x 129S1)F1] was used.  BALB/cA congenic line. C57BL/6 background is available at RBRC09728.</ns1:strainDevelopment>
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    <dc:description xml:lang="ja">ヒストンバリアントHist1h2aaとHist1h2baの両遺伝子を含む3.6 kbの領域をNeoに置き換えたKOマウス。ホモ接合体のオスは不妊。ホモ接合体メス由来の胚の約半数は、初期胚のうちに発生が停止する。ヘテロ接合体の個体を繁殖に使用。</dc:description>
    <ns4:termsAndConditions xml:lang="en">In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Stem Cell., 14, 217-227 (2014). Development, 142, 1287-1292 (2015).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with RIKEN BRC and must obtain a prior written consent from the RIKEN BRC.  RECIPIENT must contact the RIKEN BRC in the case of application for any patents or commercial use based on the results from use of the BIOLOGICAL RESOURCE.</ns4:termsAndConditions>
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    <ns4:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;研究成果の公表にあたって譲渡者の指定する文献を引用する。Cell Stem Cell., 14, 217-227 (2014). Development, 142, 1287-1292 (2015).&lt;br&gt;研究成果の公表にあたって謝辞の表明を必要とする。&lt;br&gt;営利機関の利用希望者は、事前に利用条件等につき理研BRCと合意し、提供承諾を得ること。利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、理研BRCと別途協議を行う。</ns4:termsAndConditions>
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