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MineSummary [1ap6]

Summary Structural Experimental Function Sequence Neighbor Download Link

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PDB ID1ap6  sequence information (FASTA format)   
DescriptorMANGANESE SUPEROXIDE DISMUTASE
TitleTYR34->PHE MUTANT OF HUMAN MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE
Functional KeywordsOXIDOREDUCTASE, MANGANESE, TRANSIT PEPTIDE
Biological sourceHomo sapiens (human)
Cellular location [UNP - P04179] Mitochondrion matrix
Organ sourceKIDNEY
Total number of polymer chains2
Total molecular weight44544.4 (the details in Structural Details Page)
AuthorsGuan, Y. , Tainer, J.A. (deposition date : 1997-07-24, release date : 1998-01-28)
Primary citationGuan, Y. , Hickey, M.J. , Borgstahl, G.E. , Hallewell, R.A. , Lepock, J.R. , O'Connor, D. , Hsieh, Y. , Nick, H.S. , Silverman, D.N. , Tainer, J.A.
Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34.
Biochemistry, 37:4722 - 4730, 1998.(PubMed : 9537987)  (DOI: 10.1021/bi972394l)
Experimental methodX-RAY DIFFRACTION ( 1.90[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P04179 ) , eF-site , KEGG ( EC 1.15.1.1 ) , PISA