PDB ID 1npv sequence information (FASTA format)
Descriptor POL polyprotein [Contains: Protease, {1-BENZYL-3-[2-BENZYL-3-OXO-4-(1-OXO-1,2,3,4-TETRAHYDRO- ISOQUINOLIN-4-YL)-2,3-DIHYDRO-1H-PYRROL-2-YL]-2- HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER
Title Crystal structure of HIV-1 protease complexed with LDC271
Functional Keywords Protease, Hydrolase
Biological source Human immunodeficiency virus 1
Total number of polymer chains 2
Total molecular weight 22203.3 (the details in Structural Details Page )
Authors Smith, A.B.
(deposition date : 2003-01-20, release date : 2003-02-04)
Primary citation Smith, A.B. , Cantin, L.D. , Pasternak, A. , Guise-Zawacki, L. , Yao, W. , Charnley, A.K. , Barbosa, J. , Sprengeler, P.A. , Hirschmann, R. , Munshi, S. , Olsen, D.B. , Schleif, W.A. , Kuo, L.C.J.Med.Chem. ,
46:1831 - 1844, 2003.(PubMed : 12723947) (DOI: 10.1021/jm0204587)
Experimental method X-RAY DIFFRACTION ( 2.[Å] )
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