PDB ID 1s1x sequence information (FASTA format)
RELATED PDB ID 1vrt , 1rth , 1vru , 1rti , 1rtj , 1rev , 1rt1 , 1rt2 , 1klm , 1rt3 , 1rt4 , 1rt5 , 1rt6 , 1rt7 , 1c0t , 1c0u , 1c1b , 1c1c , 1dtq , 1dtt , 1ep4 , 1fk9 , 1fko , 1fkp , 1jla , 1jlb , 1jlc , 1jle , 1jlf , 1jlg , 1jkh , 1jlq , 1lw0 , 1lw2 , 1lwc , 1lwe , 1lwf , 1s1t , 1s1u , 1s1v , 1s1w
Descriptor Reverse transcriptase (EC 2.7.7.49)
Title Crystal structure of V108I mutant HIV-1 reverse transcriptase in complex with nevirapine
Functional Keywords HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, NEVIRAPINE, DRUG RESISTANCE MUTATIONS, TRANSFERASE
Biological source Human immunodeficiency virus 1
Cellular location
[UNP - P04585 ]
Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential)
Total number of polymer chains 2
Total molecular weight 116289.7 (the details in Structural Details Page )
Authors Ren, J. , Nichols, C.E. , Chamberlain, P.P. , Stammers, D.K.
(deposition date : 2004-01-07, release date : 2004-06-29)
Primary citation Ren, J. , Nichols, C.E. , Chamberlain, P.P. , Weaver, K.L. , Short, S.A. , Stammers, D.K.J.Mol.Biol. ,
336:569 - 578, 2004.(PubMed : 15095972) (DOI: 10.1016/j.jmb.2003.12.055)
Experimental method X-RAY DIFFRACTION ( 2.80[Å] )
Other Database Information
