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<Asymmetric unit>

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PDB ID2jm5  sequence information (FASTA format)   
DescriptorRegulator of G-protein signaling 18
TitleSolution Structure of the RGS domain from human RGS18
Functional Keywordssignaling protein, Structural Genomics, Structural Genomics Consortium, SGC
SIGNALING PROTEIN
Biological sourceHomo sapiens (human)
Cellular location [UNP - Q9NS28] Cytoplasm (By similarity)
Organ source [UNP - Q9NS28] Platelet
[UNP - Q9NS28] Liver
Total number of polymer chains1
Total molecular weight17786.2 (the details in Structural Details Page)
AuthorsHigman, V.A. , Leidert, M. , Bray, J. , Elkins, J. , Soundararajan, M. , Doyle, D.A. , Gileadi, C. , Phillips, C. , Schoch, G. , Yang, X. , Brockmann, C. , Schmieder, P. , Diehl, A. , Sundstrom, M. , Arrowsmith, C. , Weigelt, J. , Edwards, A. , Oschkinat, H. , Ball, L.J. , Structural Genomics Consortium (SGC) (deposition date : 2006-10-11, release date : 2006-10-24)
Primary citationSoundararajan, M. , Willard, F.S. , Kimple, A.J. , Turnbull, A.P. , Ball, L.J. , Schoch, G.A. , Gileadi, C. , Fedorov, O.Y. , Dowler, E.F. , Higman, V.A. , Hutsell, S.Q. , Sundstrom, M. , Doyle, D.A. , Siderovski, D.P.
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105:6457 - 6462, 2008.(PubMed : 18434541)  (DOI: 10.1073/pnas.0801508105)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9NS28 ) , eF-site , PISA , NRG-CING