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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1bx2  sequence information (FASTA format)   
DescriptorPROTEIN (HLA-DR2)
TitleCRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101,DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN
Functional KeywordsHLA-DR2, MYELIN BASIC PROTEIN, MULTIPLE SCLEROSIS, AUTOIMMUNITY, IMMUNE SYSTEM
Biological sourceHomo sapiens (human)
Cellular location [UNP - P01903] Membrane; Single-pass type I membrane protein
Organ source [UNP - P01903] Blood, and Colon
[UNP - P01903] B-cell
[UNP - P01903] Blood
[UNP - P04229] Cerebellum
Total number of polymer chains6
Total molecular weight90620.6 (the details in Structural Details Page)
AuthorsSmith, K.J. , Pyrdol, J. , Gauthier, L. , Wiley, D.C. , Wucherpfennig, K. (deposition date : 1998-10-12, release date : 1998-10-21)
Primary citationSmith, K.J. , Pyrdol, J. , Gauthier, L. , Wiley, D.C. , Wucherpfennig, K.W.
Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein.
J.Exp.Med., 188:1511 - 1520, 1998.(PubMed : 9782128)  (DOI: 10.1084/jem.188.8.1511)
Experimental methodX-RAY DIFFRACTION ( 2.6[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01903, P04229 ) , eF-site , PISA