PDB ID 1bx2 sequence information (FASTA format)
Descriptor PROTEIN (HLA-DR2)
Title CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101,DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN
Functional Keywords HLA-DR2, MYELIN BASIC PROTEIN, MULTIPLE SCLEROSIS, AUTOIMMUNITY, IMMUNE SYSTEM
Biological source Homo sapiens
(human)
Cellular location
[UNP - P01903 ]
Membrane; Single-pass type I membrane protein
Organ source
[UNP - P01903 ]
Blood, and Colon
[UNP - P01903 ]
B-cell
[UNP - P01903 ]
Blood
[UNP - P04229 ]
Cerebellum
Total number of polymer chains 6
Total molecular weight 90620.6 (the details in Structural Details Page )
Authors Smith, K.J. , Pyrdol, J. , Gauthier, L. , Wiley, D.C. , Wucherpfennig, K.
(deposition date : 1998-10-12, release date : 1998-10-21)
Primary citation Smith, K.J. , Pyrdol, J. , Gauthier, L. , Wiley, D.C. , Wucherpfennig, K.W. Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein.
J.Exp.Med. ,
188:1511 - 1520, 1998.(PubMed : 9782128) (DOI: 10.1084/jem.188.8.1511)
Experimental method X-RAY DIFFRACTION ( 2.6[Å] )
Other Database Information