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<Asymmetric unit>
= <Biological unit>

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PDB ID1tbz  sequence information (FASTA format)   
DescriptorALPHA-THROMBIN, HIRUGEN, N-METHYL-D PHENYLALANYL-N-[5-(AMINOIMINOMETHYL) AMINO]-1-[(BENZOTHIAZOLYL)CARBONYL]BUTYL-L-PROLINAMIDE TRIFLUROACETATE, BENZOTHIAZOLE
TitleHUMAN THROMBIN WITH ACTIVE SITE N-METHYL-D PHENYLALANYL-N-[5-(AMINOIMINOMETHYL)AMINO]-1-{{BENZOTHIAZOLYL)CARBONYL] BUTYL]-L-PROLINAMIDE TRIFLUROACETATE AND EXOSITE-HIRUGEN
Functional KeywordsCOMPLEX (SERINE PROTEASE/INHIBITOR)
Biological sourceHomo sapiens (human) ,Hirudo medicinalis (medicinal leech) (the details in Structural Details Page)
Cellular location [UNP - P00734] Secreted, extracellular space
[UNP - P09945] Secreted
Organ source [UNP - P00734] Mammary gland
[UNP - P00734] Plasma
Total number of polymer chains4
Total molecular weight36026.3 (the details in Structural Details Page)
AuthorsMatthews, J.H. , Krishnan, R. , Costanzo, M.J. , Maryanoff, B.E. , Tulinsky, A. (deposition date : 1998-02-05, release date : 1998-05-27)
Primary citationMatthews, J.H. , Krishnan, R. , Costanzo, M.J. , Maryanoff, B.E. , Tulinsky, A.
Crystal structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.
Biophys.J., 71:2830 - 2839, 1996.(PubMed : 8913620)
Experimental methodX-RAY DIFFRACTION ( 2.3[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00734, P09945 ) , eF-site , KEGG ( EC 3.4.21.5 ) , PISA