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MineSummary [1z7j]

[1z7j] replaced from '1ked'

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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PDB ID1z7j  sequence information (FASTA format)   
RELATED PDB ID1pab, 2rox
DescriptorTransthyretin
TitleHuman transthyretin (also called prealbumin) complex with 3, 3',5,5'-tetraiodothyroacetic acid (t4ac)
Functional KeywordsALBUMIN, TRANSPORT, RETINOL-BINDING, VITAMIN A, AMYLOID, THYROID HORMONE, LIVER, PLASMA, CEREBROSPINAL FLUID, POLYNEUROPATHY, POLYMORPHISM, DISEASE MUTATION, TETRAIODOTHYROACETIC ACID, T4AC, PREALBUMIN, TRANSPORT PROTEIN
Biological sourceHomo sapiens (human)
Cellular location [UNP - P02766] Secreted
Organ source [UNP - P02766] Liver
[UNP - P02766] Platelet
[UNP - P02766] Brain, Cajal-Retzius cell, and Fetal brain cortex
[UNP - P02766] Plasma
[UNP - P02766] Cerebrospinal fluid
Total number of polymer chains2
Total molecular weight29050.6 (the details in Structural Details Page)
AuthorsNeumann, P. , Wojtczak, A. , Cody, V. (deposition date : 2005-03-25, release date : 2005-06-07)
Primary citationNeumann, P. , Cody, V. , Wojtczak, A.
Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution.
Acta Crystallogr.,Sect.D, 61:1313 - 1319, 2005.(PubMed : 16204882)  (DOI: 10.1107/S0907444905022523)
Experimental methodX-RAY DIFFRACTION ( 2.20[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P02766 ) , eF-site , PISA